Cell Migration - The Nucleus and Rear

The Nucleus and Rear

Given that a cell’s front advances, what about the rest of the cell? Is it simply dragged forward, like a sack? This information is not known, but there are suggestions that the nucleus and perhaps other large structures inside the cell may also be pulled forward by actin filaments. In addition, it may be that the rear of the cell actively contracts, as it is here that, in some cells, the major contractile protein myosin is found.

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