Early Life and College Playing Career
Isbell was born in Houston, Texas, the second son of Adger and Sarah Isbell. His older brother Cody was also a football player for Purdue. Cecil also had two younger brothers who played college football, "Dub" Isbell at Rice University and Larry Isbell at Baylor University. Cecil attended Sam Houston High School in Houston. Cecil played for Purdue from 1935 through 1937. He was voted the Boilermakers' most valuable player for the 1937 season. In the summer of 1938, he led the College All-Stars to victory over the NFL champion Washington Redskins at Soldier Field in Chicago. Isbell was named the game's MVP as the All-Stars prevailed, 28–16.
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