CCL4 - Function

Function

CCL4, also known as Macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells.

CCL4 is a major HIV-suppressive factor produced by CD8+ T cells.

Perforin-low memory CD8+ T cells that normally synthesize MIP-1-beta.

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