MCD Symptoms
The most common 'B Symptoms' of MCD are high fevers, anemia, weight loss, loss of appetite, and low white blood cell counts, which may to be due to the overproduction of interleukin 6. Symptomatically, therefore, MCD can be difficult to diagnose and even in the case of a lymph-node biopsy a conclusive diagnosis remains problematic.
Castleman's is seen in POEMS syndrome and is implicated in 10% of cases of paraneoplastic pemphigus.
Read more about this topic: Castleman's Disease
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