The name Castello Branco may refer to
- Camilo Castelo Branco (1825–1890); Portuguese writer, publishing over 260 works in this time; committed suicide in 1890.
- Humberto de Alencar Castello Branco (1897–1967); Brazilian marshal, involved in the 1964 coup d'état, and President of Brazil from 1964 to 1967.