Cancer Immunotherapy - Cell Based Immunotherapy

Cell Based Immunotherapy

Adoptive Cell based Immunotherapy was first introduced by Rosenberg and his Colleagues of NIH, USA and it is now widely being used in various countries. It involves isolation of either allogenic or autologous immune cells, enriching them outside the body and transfusing them back to the patient. The injected immune cells are highly cytotoxic to the Cancer cells thereby helping to fight the cancer cells. This therapy is in routine clinical practice in Japan and Autologous immune enhancement therapy involving Natural Killer Cells (NK) cells and cytotoxic T Lymphocytes(CTLs) is being practised in various Asian Countries especially in Japan and Malaysia . In addition, a method derived from the adoptive cell based therapy ideas begun by Rosenberg et al. called ALECSAT is currently undergoing phase I clinical trials in Denmark.

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