Canavan disease, also called Canavan-Van Bogaert-Bertrand disease, aspartoacylase deficiency or aminoacylase 2 deficiency, is an autosomal recessive degenerative disorder that causes progressive damage to nerve cells in the brain. Canavan disease is also one of the most common degenerative cerebreal diseases of infancy. This disease is one of a group of genetic disorders called leukodystrophies.
Leukodystrophies are characterized by degeneration of myelin in the phospholipid layer insulating the axon of a neuron. The gene associated with the disorder is located on human chromosome 17.
Read more about Canavan Disease: Prevalence, Pathophysiology, Symptoms, Treatment, Prognosis, Current Research
Famous quotes containing the word disease:
“What is the disease which manifests itself in an inability to leave a partyany party at alluntil it is all over and the lights are being put out?... I suppose that part of this mania for staying is due to a fear that, if I go, something good will happen and Ill miss it. Somebody might do card tricks, or shoot somebody else.”
—Robert Benchley (18891945)