Pharmaceutical Manufacture
Calcitonin was extracted from the Ultimobranchial glands (thyroid-like glands) of fish, particularly salmon. Salmon calcitonin resembles human calcitonin, but is more active. At present, it is produced either by recombinant DNA technology or by chemical peptide synthesis. The pharmacological properties of the synthetic and recombinant peptides have been demonstrated to be qualitatively and quantitatively equivalent.
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“The great cry that rises from all our manufacturing cities, louder than the furnace blast, is all in very deed for this—that we manufacture everything there except men.”
—John Ruskin (1819–1900)