Caisse, a French word, may refer to:
- Andy Caisse, a Canadian political activist
- Caisse Desjardins, an association of credit unions in Quebec
- Caisse d'Epargne-Illes Balears, a road-bicycle racing team
- Caisse de dépôt et placement du Québec, a public pension fund in Quebec
- Caisse nationale suisse d'assurance en cas d'accidents, a Swiss insurer
- Caisse de Stabilisation des Prix du Coton, a Chadian government agency
- Mouvement des caisses populaires acadiennes, a credit union in the Canadian province of New Brunswick