History and Nomenclature
CRP was so named because it was first discovered as a substance in the serum of patients with acute inflammation that reacted with the C-polysaccharide of pneumococcus.
Discovered by Tillett and Francis in 1930, it was initially thought that CRP might be a pathogenic secretion as it was elevated in people with a variety of illnesses including cancer, however, discovery of hepatic synthesis demonstrated that it is a native protein.
Read more about this topic: C-reactive Protein
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