Physiology
The process of filtration of the blood in the Bowman's capsule is ultrafiltration (or glomerular filtration), and the normal rate of filtration is 125 ml/min, equivalent to 80 times the daily blood volume.
Any proteins under roughly 30 kilodaltons can pass freely through the membrane, although there is some extra hindrance for negatively charged molecules due to the negative charge of the basement membrane and the podocytes.
Any small molecules such as water, glucose, salt (NaCl), amino acids, and urea pass freely into Bowman's space, but cells, platelets and large proteins do not.
As a result, the filtrate leaving the Bowman's capsule is very similar to blood plasma in composition as it passes into the proximal convoluted tubule.
Read more about this topic: Bowman's Capsule
Famous quotes containing the word physiology:
“The world moves, but we seem to move with it. When I studied physiology before ... there were two hundred and eight bones in the body. Now there are two hundred and thirty- eight.”
—Ellen Henrietta Swallow Richards (1842–1911)
“Now the twitching stops. Now you are still. We are through with physiology and theology, physics begins.”
—Alfred Döblin (1878–1957)
“A physician’s physiology has much the same relation to his power of healing as a cleric’s divinity has to his power of influencing conduct.”
—Samuel Butler (1835–1902)