The term Boule may refer to:
- Boule (ancient Greece), plural boulai, an assembly forming part of city governments in Ancient Greece
- Boule (crystal), a block of synthetically produced crystal material
- Boule (gene), an alias for the gene BOLL, responsible for sperm production in animals
- Boule (community), a community of the Ivory Coast, West Africa
- Boule (bread), a round loaf of white (often sourdough) bread, from boule, the French word for 'ball'
- Marcellin Boule (1861–1942), French palaeontologist
- Boules, in full jeu de boules, a collective term for ball games involving metal balls aimed at a smaller target ball
- Boule ton Ellinon, a term for the Hellenic Parliament
- Boule et Bill, a Belgian comic book series, created in 1959
- "Boule de Suif", a 1884 short story by Guy de Maupassant
- "Coup de Boule" (French for "headbutt"), a 2006 French song
- Sigma Pi Phi, a historically black fraternity in the United States