Plasma Shift
Blood plasma volume may be expanded by or drained to extravascular fluid when there are changes in Starling forces across capillary walls. For example, when blood pressure drops in circulatory shock, Starling forces drive fluid into the interstitium, causing "third spacing."
If one stands still for a prolonged period, this causes an increase in transcapillary hydrostatic pressure. As a result, approximately 12% of blood plasma volume crosses into the extravascular compartment. This causes an increase in hematocrit, serum total protein, blood viscosity and, as a result of increased concentration of coagulation factors, it causes orthostatic hypercoagulability.
Read more about this topic: Blood Plasma
Famous quotes containing the word shift:
“The frantic search of five-year-olds for friends can thus be seen to forecast the beginnings of a basic shift in the parent-child relationship, a shift which will occur gradually over many long years, and in which a child needs not only the support of child allies engaged in the same struggle but also the understanding of his parents.”
—Dorothy H. Cohen (20th century)