Biotinidase Deficiency - Epidemiology

Epidemiology

Based on the results of worldwide screening of biotinidase deficiency in 1991, the incidence of the disorder is:

• One in 137,401 for profound biotinidase deficiency
• One in 109,921 for partial biotinidase deficiency
• One in 61,067 for the combined incidence of profound and partial biotinidase deficiency
• Carrier frequency in the general population is approximately one in 120.