Biosafety Level - List of BSL-4 Facilities

List of BSL-4 Facilities

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According to the United State Government Accountability Office (GAO) report published on October 4, 2007, a total of 1356 CDC/USDA registered BSL-3 facilities were identified throughout the United States (GAO-08-108T ). This represents a very conservative estimate of the number of facilities in the US in 2007. Approximately 36% of these laboratories are located in academia. Only 15 BSL-4 facilities were identified at the time, including 9 at federal labs.

Name Location Level Established Discontinued Description
Virology Laboratory of the Queensland Department of Health Australia, Queensland, Coopers Plains 4
University of Queensland - Sir Albert Sakzewski Virus Research Centre (SASVRC) Royal Women's Hospital Brisbane P3 (BL3) Australia, Queensland, Herston 3+4
Australian Animal Health Laboratory Australia, Victoria, Geelong 4
National High Security Laboratory Australia, Victoria, North Melbourne 4 National High Security Laboratory Operates under the auspice of the Victoria Infectious Diseases Reference Laboratory.
Republican Research and Practical Center for Epidemiology and Microbiology Belarus, Minsk 4 Department of Molecular Epidemiology & Innovational Biotechnologies
National Microbiology Laboratory Canada, Manitoba, Winnipeg 4 Located at the Canadian Science Centre for Human and Animal Health, it is jointly operated by the Public Health Agency of Canada and the Canadian Food Inspection Agency.
Wuhan Institute of Virology of the Chinese Academy of Sciences China, Hubei, Wuhan 3 - 4 2010 (P4) Wuhan Institute of Virology already hosts a BSL-3 laboratory. A distinct BSL-4 facility is currently being built based on P4 standards, the original technology for confinement developed by France. It will be the first at level 4 in China, under the direction of Shi Zhengli.
Biological Defense Center Czech Republic, Pardubice, Těchonín 4 Located at the Centrum biologické ochrany (Biological Defense Center)
Laboratoire P4 Jean Mérieux France, Rhône-Alpes, Lyon 4 1999-03-05 Jean Mérieux laboratory is a co-operation between the Pasteur Institute and INSERM. Note that in France, it is P4 for Pathogen or Protection level 4.
Centre International de Recherches Médicales de Franceville Gabon 4 This facility is operated by a research organization supported by both Gabonese (mainly) and French governments, and is West Africa's only P4 lab (BSL-4).
Robert Koch Institute Germany, Berlin 4 The facility was licenced for construction by City of Berlin on November 30, 2008.
Bernhard Nocht Institute for Tropical Medicine Germany, Hamburg 4
Friedrich Loeffler Institute on the Isle of Riems Germany, Isle of Riems (Greifswald) 4 2010 Deals especially with virology
Philipps University of Marburg Germany, Marburg 4 2008 The facility is licenced to work with genetically modified organisms
High Security Animal Disease Laboratory (HSADL) India, Bhopal 4 1998 This facility deals especially to zoonotic organisms and emerging infectious disease threats.
Centre for Cellular and Molecular Biology India, Hyderabad 4 2009 National Bio-Safety Level-4 Containment Facility for Human Infectious Diseases & Clinical Research Facility in Regenerative Medicine
All India Institute of Medical Sciences India, New Delhi 1-4 1993 Conducts studies on major pathogenic organisms. Has contributed in discovering new strains & vaccines.
Azienda Ospedaliera Ospedale Luigi Sacco Italy, Lombardy, Milan 4 A university hospital in Polo Universitario; it contains two special vehicles for transporting infectious persons.
Istituto Nazionale Malattie Infettive Italy, Rome, Rome 4 This facility, (trans.) National Institute of Infectious Diseases, operates within the Lazzaro Spallanzani Hospital.
National Institute for Infectious Diseases Japan, Kantō, Tokyo 3 (4) Located at National Institute for Infectious Diseases, Department of Virology I; this lab has the potential of operating as a BSL-4, however it is limited to perform work on only BSL-3 agents due to opposition from local residents and communities.
Institute of Physical and Chemical Research Japan, Kantō, Tsukuba (4) This is a non-operating BSL-4 facility.
Netherlands National Institute for Public Health and the Environment (RIVM) Netherlands, Bilthoven 3 - 4 2009
Cantacuzino Microbiological Research Institute (INCDMI) Romania, Bucharest 4
"Dr. Carol Davila" Central Military Hospital Romania, Bucharest 3 - 4
State Research Center of Virology and Biotechnology VECTOR Russia, Novosibirsk Oblast, Koltsovo 1 - 4 It is one of two facilities in the world that officially hold smallpox. The other Russian BSL-4 facilities have been dismantled.
National Institute for Communicable Diseases South Africa, Johannesburg 4 National Institute for Communicable Diseases of Special Pathogens Unit is one of only two BSL-4 facilities in Africa but the only suit laboratory on the continent.
Swedish Institute for Communicable Disease Control Sweden, Solna 4 Swedish Institute for Communicable Disease Control is Scandinavia's P4 facility.
Institute of Virology and Immunoprophylaxis (IVI) Switzerland, Mittelhäusern 4 2007-02-01 This facility only deals with animal diseases which do not transmit to humans, and is the only P4 facility where complete isolation suits are not used.
High Containment Laboratory DDPS (SiLab) Switzerland, Spiez 4 Under construction, it will start operations in 2010. This laboratory will comply with BSL-4 standards.
Kwen-yang Laboratory (昆陽實驗室) Center of Disease Control Taiwan 4 Part of the Department of Health, Taiwan.
Preventive Medical Institute of ROC Ministry of National Defense Taiwan 4
Health Protection Agency's Centre for Infections United Kingdom, Colindale 4 Located in the Viral Zoonosis unit.
National Institute for Medical Research United Kingdom, London 4
Institute for Animal Health United Kingdom, Pirbright 4
Defence Science and Technology Laboratory United Kingdom, Porton Down 4
Health Protection Agency United Kingdom, Porton Down 4 Special Pathogens Reference Unit.
Health Protection Agency United Kingdom, Porton Down 4 Botulism.
Centers for Disease Control and Prevention United States, Georgia, Atlanta 4 Currently operates in two buildings. One of two facilities in the world that officially hold smallpox.
Georgia State University United States, Georgia, Atlanta 4 Is an older design "glovebox" facility.
National Bio and Agro-Defense Facility (NBAF), Kansas State University United States, Kansas, Manhattan 4 Facility to be operated by the Department of Homeland Security, and replace the Plum Island Animal Disease Center. Planned to be operational by 2014.
National Institutes of Health (NIH) United States, Maryland, Bethesda 4 Located on the NIH Campus, it currently only operates with BSL-3 agents.
Integrated Research Facility United States, Maryland, Fort Detrick 4 Under construction. This facility will be operated by National Institute of Allergy and Infectious Diseases (NIAID), it is planned to begin operating at 2009 at the earliest.
National Biodefense Analysis and Countermeasures Center (NBACC) United States, Maryland, Fort Detrick 4 Under construction, it will be operated for the Department of Homeland Security.
US Army Medical Research Institute of Infectious Diseases (USAMRIID) United States, Maryland, Fort Detrick 4 Old building
US Army Medical Research Institute of Infectious Diseases (USAMRIID) United States, Maryland, Fort Detrick 4 New building, currently under design construction
National Emerging Infectious Diseases Laboratory (NEIDL), Boston University United States, Massachusetts, Boston 4 Under construction by Boston University, building and staff training complete, waiting for regulatory approval.
NIAID Rocky Mountain Laboratories United States, Montana, Hamilton 4 National Institute of Allergy and Infectious Diseases
Kent State University, Kent Campus United States, Ohio, Kent 3-4 Operates as a clean lab at level 3 for training purposes. Scheduled for conversion to a hot level 4 lab in response to a bioterrorism event in the USA.
Galveston National Laboratory, National Biocontainment Facility United States, Texas, Galveston 4 Opened in 2008, facility is operated by the University of Texas Medical Branch.
Shope Laboratory United States, Texas, Galveston 4 Operated by the University of Texas Medical Branch (UTMB).
Texas Biomedical Research Institute United States, Texas, San Antonio 3+4 The only privately owned BSL-4 lab in the US.
Division of Consolidated Laboratory Services United States, Virginia, Richmond 4 This facility is part of the Department of General Services of the Commonwealth of Virginia. It is so called "surge" BSL-4 capacity.

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