Adverse Effects
The benefits—as well as adverse effects—are expected to be the same for bioidentical and synthetic hormones. Dosages used in BHRT can be as high as ten times the oral dose provided by comparable HRT regimens; the hormones used are known to adversely impact biological markers of cardiovascular disease, and may produce a substantially higher risk of heart attack or stroke because of this. There are potentially serious adverse effects and important safety information which is required to be given with FDA approved HRT in the form of package inserts; however, package inserts are typically not given (or required) with compounded bioidentical preparations. This has led consumers into the erroneous assumption that bioidenticals are safer than FDA-approved hormones or lack any adverse effects—one of the concerns expressed about the hormones. BHRT has also been associated with endometrial cancer.
Read more about this topic: Bioidentical Hormone Replacement Therapy
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