Beano (dietary Supplement) - Mechanism of Action

Mechanism of Action

Beano is a product containing the enzyme alpha galactosidase, which is derived from the fungus Aspergillus niger. The enzyme works in the digestive tract to break down the complex or branching sugars (polysaccharides and oligosaccharides) in foods such as legumes (beans and peanuts) and cruciferous vegetables (cauliflower, broccoli, cabbage, brussels sprouts, among others). The enzyme breaks those complex sugars into simple sugars, making these foods somewhat more digestible, and reducing intestinal gas.

The polysaccharides and oligosaccharides found in these foods might otherwise pass through the small intestine unaffected. Once in the large intestine, those sugars may be metabolized by intestinal flora, fermenting to produce the gases that cause discomfort.

Two randomized controlled trials show reduction in gas by subjects taking oral alpha galactosidase. Another study indicates alpha galactosidase may interfere with the diabetic medication acarbose.

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