Bayliss may refer to:
- Places
- Bayliss, California, in Glenn County
- People
- Adam Bayliss, film producer
- Brendan Bayliss, musician
- David Bayliss, footballer
- Edward Bayliss, cricketer
- Garland E. Bayliss, historian
- George Bayliss, Australian Rules footballer
- John Bayliss, poet and editor
- Jonah Bayliss, baseball player
- Jonathan Bayliss, novelist and playwright
- Lisa Bayliss, field hockey player
- Mark Bayliss, Australian Rules footballer
- Simon Bayliss, musician
- Troy Bayliss, motorcycle racer
- William Bayliss, physiologist
- Wyke Bayliss, painter, author, and poet
- Bayliss Levrett, racing driver
- Fictional characters
- Jim Bayliss/Sue Bayliss, in All My Sons
- Tim Bayliss, a fictional character in TV show Homicide: Life on the Street
- Other uses
- Bayliss Avenue, football stadium in London
- Bayliss Effect, physiological process discovered by William Bayliss