Bacterial Capsule - Diversity

Diversity

The capsule is found most commonly among Gram-negative bacteria:

  • Escherichia coli (in some strains)
  • Klebsiella pneumoniae
  • Haemophilus influenzae
  • Pseudomonas aeruginosa (more accurately described as a slime layer)
  • Salmonella

However, some Gram-positive bacteria may also have a capsule:

  • Bacillus megaterium for example, synthesizes a capsule composed of polypeptide and polysaccharides.
  • Streptococcus pyogenes synthesizes a hyaluronic acid capsule.
  • Streptococcus pneumoniae
  • Streptococcus agalactiae produces a polysaccharide capsule of nine antigenic types that all contain sialic acid (Ia, Ib, II, III, IV, V, VI, VII, VIII).
  • Staphylococcus epidermidis

The yeast Cryptococcus neoformans, though not a bacterium, has a similar capsule.

Capsules too small to be seen with an ordinary microscope, such as the M protein of Streptococcus pyogenes, are called microcapsules.

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