Genome Structure
B. anthracis has a single chromosome which is a circular, 5,227,293 bp DNA molecule. It also has two circular, extrachromosomal, double-stranded DNA plasmids, pXO1 and pXO2. Both the pXO1 and pXO2 plasmids are required for full virulence and represent two distinct plasmid families.
| Feature | Chromosome | pXO1 | pXO2 |
|---|---|---|---|
| Size (bp) | 5,227,293 | 181,677 | 94,829 |
| Number of genes | 5,508 | 217 | 113 |
| Replicon coding (%) | 84.3 | 77.1 | 76.2 |
| Average gene length (nt) | 800 | 645 | 639 |
| G+C content (%) | 35.4 | 32.5 | 33.0 |
| rRNA operons | 11 | 0 | 0 |
| tRNAs | 95 | 0 | 0 |
| sRNAs | 3 | 2 | 0 |
| Phage genes | 62 | 0 | 0 |
| Transposon genes | 18 | 15 | 6 |
| Disrupted reading frame | 37 | 5 | 7 |
| Genes with assigned function | 2,762 | 65 | 38 |
| Conserved hypothetical genes | 1,212 | 22 | 19 |
| Genes of unknown function | 657 | 8 | 5 |
| Hypothetical genes | 877 | 122 | 51 |
Read more about this topic: Bacillus Anthracis
Famous quotes containing the word structure:
“The verbal poetical texture of Shakespeare is the greatest the world has known, and is immensely superior to the structure of his plays as plays. With Shakespeare it is the metaphor that is the thing, not the play.”
—Vladimir Nabokov (1899–1977)