Azteca may refer to:
- Azteca (band), a Latin based rock band from the San Francisco Bay Area, United States
- Azteca (horse), a breed of horse
- Azteca (genus), a genus of ants
- Azteca Records (California), a record label
- Azteca Records (New Jersey), a record label
- Azteca Mexican Restaurants, a chain located in the United States
- Azteca Foods, Inc., a tortilla and chip manufacturer located in Chicago, Illinois
- Azteca Productions, independent comic book publisher
- The "Aztecas" collegiate athletics teams of Fundación Universidad de las Américas, Puebla (Cholula, Mexico)
- Estadio Azteca, a sports stadium in Mexico City, Mexico
- Adidas Azteca, the official match ball of 1986 FIFA World Cup in Mexico
- Líneas Aéreas Azteca, a Mexican airline
- TV Azteca, a Mexican television network