Axl may refer to: professional wrestler
- Axl Rose, lead singer of Guns N' Roses
- Axl Low, a character in the Guilty Gear video game series
- AXL receptor tyrosine kinase in biochemistry, a member of the receptor tyrosine kinase family of cell surface receptors
- AXL Guitars, a guitar manufacturing company
- Axl Heck, a fictional character from the television sitcom, "The Middle"