Atrial Septal Defect - Associated Conditions

Associated Conditions

  • Down Syndrome - patients with Down Syndrome have higher rates of ASDs, especially a particular type that involves the ventricular wall. As many as one half of Down Syndrome patients have some type of septal defect.
  • Ebstein's anomaly
  • Fetal alcohol syndrome - about one in four patients with fetal alcohol syndrome has either an ASD or a ventricular septal defect.
  • Holt–Oram syndrome - Both the osteium secundum and osteum primum types of ASD are associated with Holt–Oram syndrome
  • Lutembacher's syndrome - the presence of a congenital ASD along with acquired mitral stenosis.

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