Astragalus - Research

Research

The biotechnology firms Geron Corporation and TA Therapeutics of Hong Kong have been working on deriving a telomerase activator from it. The chemical constituent cycloastragenol (also called TAT2) is being studied to help combat HIV, as well as infections associated with chronic diseases or aging. However, the National Institutes of Health states: "The evidence for using astragalus for any health condition is limited. High-quality clinical trials (studies in people) are generally lacking. There is some preliminary evidence to suggest that astragalus, either alone or in combination with other herbs, may have potential benefits for the immune system, heart, and liver, and as an adjunctive therapy for cancer".

In a study published in the 15 November 2008 Journal of Immunology, researchers shed light on the antiviral and antiaging benefits of Astragalus. In their paper, a team of researchers from the UCLA AIDS Institute described how their work with cycloastragenol reduces the aging process of immune cells, and enhances how these cells respond to viral infections. The compound works by boosting production of telomerase, an enzyme that allows for the replacement of short bits of DNA, known as telomeres, that play a key role in cell replication, cancer and human aging.

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