Signs and Symptoms
Most commonly, the first symptom is rhinitis (inflammation or irritation of the nasal mucosa), which can manifest with symptoms of sneezing, runny nose, or congestion. The disorder typically progresses to asthma, then nasal polyposis, with aspirin sensitivity coming last. The reactions to aspirin vary, but can be severe, ranging from mild nasal congestion and eye watering to lower respiratory symptoms including wheezing, coughing, an asthma attack, anaphylaxis, and urticaria in some cases. Patients typically react to other NSAIDs such as ibuprofen, and any medication that inhibits the COX-1 enzyme, although paracetamol (acetaminophen) in low doses is generally considered safe.
Anosmia (lack of smell) is also common, as the inflammation reaches the olfactory receptors in the nose.
Read more about this topic: Aspirin-induced Asthma
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