Signs and Symptoms
Most commonly, the first symptom is rhinitis (inflammation or irritation of the nasal mucosa), which can manifest with symptoms of sneezing, runny nose, or congestion. The disorder typically progresses to asthma, then nasal polyposis, with aspirin sensitivity coming last. The reactions to aspirin vary, but can be severe, ranging from mild nasal congestion and eye watering to lower respiratory symptoms including wheezing, coughing, an asthma attack, anaphylaxis, and urticaria in some cases. Patients typically react to other NSAIDs such as ibuprofen, and any medication that inhibits the COX-1 enzyme, although paracetamol (acetaminophen) in low doses is generally considered safe.
Anosmia (lack of smell) is also common, as the inflammation reaches the olfactory receptors in the nose.
Read more about this topic: Aspirin-induced Asthma
Famous quotes containing the words signs and, signs and/or symptoms:
“For Jews demand signs and Greeks desire wisdom, but we proclaim Christ crucified, a stumbling block to Jews and foolishness to Gentiles...”
—Bible: New Testament, 1 Corinthians 1:22-3.
“Wherever I look, I see signs of the commandment to honor one’s parents and nowhere of a commandment that calls for the respect of a child.”
—Alice Miller (20th century)
“Social movements are at once the symptoms and the instruments of progress. Ignore them and statesmanship is irrelevant; fail to use them and it is weak.”
—Walter Lippmann (1889–1974)