Evolution
All aspartate proteases have a highly conserved sequence of Asp-Thr-Gly. In general, with the exception of HIV - a dimer of two identical subunits - these enzymes are monomeric enzymes consisting of two domains. Because of this organisation, it is thought that these domains may have arisen through ancestral gene duplication.
Read more about this topic: Aspartic Acid Proteases
Famous quotes containing the word evolution:
“The evolution of humans can not only be seen as the grand total of their wars, it is also defined by the evolution of the human mind and the development of the human consciousness.”
—Friedrich Dürrenmatt (1921–1990)
“The evolution of sense is, in a sense, the evolution of nonsense.”
—Vladimir Nabokov (1899–1977)
“The more specific idea of evolution now reached is—a change from an indefinite, incoherent homogeneity to a definite, coherent heterogeneity, accompanying the dissipation of motion and integration of matter.”
—Herbert Spencer (1820–1903)