Evolution
All aspartate proteases have a highly conserved sequence of Asp-Thr-Gly. In general, with the exception of HIV - a dimer of two identical subunits - these enzymes are monomeric enzymes consisting of two domains. Because of this organisation, it is thought that these domains may have arisen through ancestral gene duplication.
Read more about this topic: Aspartic Acid Proteases
Famous quotes containing the word evolution:
“The evolution of humans can not only be seen as the grand total of their wars, it is also defined by the evolution of the human mind and the development of the human consciousness.”
—Friedrich Dürrenmatt (1921–1990)
“As a natural process, of the same character as the development of a tree from its seed, or of a fowl from its egg, evolution excludes creation and all other kinds of supernatural intervention.”
—Thomas Henry Huxley (1825–95)
“What we think of as our sensitivity is only the higher evolution of terror in a poor dumb beast. We suffer for nothing. Our own death wish is our only real tragedy.”
—Mario Puzo (b. 1920)