Arroyo Hondo (Spanish: deep stream) may refer to:
- Arroyo Hondo (Santa Clara County, California), a stream
- Arroyo Hondo, New Mexico
- Arroyo Hondo, historical Spanish name for the Calcasieu River in Louisiana
- Arroyo Hondo Preserve, a nature preserve in southern Santa Barbara County, California
- Arroyo Hondo, Bolívar, a municipality in Colombia
- Arroyo Hondo, Cuba