Production
The film is largely faithful to the novel, but completely omits all mention of Arrowsmith's wealthy, self-centered second wife. Myrna Loy has only a few scenes with Colman, and their relationship is undeveloped. According to Robert Osborne, host of Turner Classic Movies, Helen Hayes noted that various scenes were dropped from the script without explanation. It turns out that Samuel Goldwyn had hired director John Ford on condition that he not drink during the production. As a result (according to Osborne), Ford sped up the filming as much as he could.
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