Argonne may refer to:
- The Forest of Argonne in France
- Argonne National Laboratory, a U.S. D.O.E. National Laboratory near Chicago, Illinois
- Meuse-Argonne Offensive, also called the Battle of Argonne Forest, a World War I battle
- Argonne, Wisconsin, a town, US
- Argonne (CDP), Wisconsin, an unincorporated community, US
- USS Argonne, a U.S. Navy auxiliary ship, commissioned in 1921
- Argonne (automobile), a short-lived U.S. car company
- Argonne Rebels, a Division I drum and bugle corps from Great Bend, Kansas
- Hotel Argonne, a historic hotel in downtown Lima, Ohio, United States