History
The LE cell was discovered in bone marrow in 1948 by Hargraves et al. This was the first indication that processes affecting the cell nucleus were responsible for lupus erythematosus (LE). In the 1950s, progressively more sensitive and specific ANA serology tests became available.
Read more about this topic: Anti-nuclear Antibody
Famous quotes containing the word history:
“The history of every country begins in the heart of a man or a woman.”
—Willa Cather (1876–1947)
“Certainly there is not the fight recorded in Concord history, at least, if in the history of America, that will bear a moment’s comparison with this, whether for the numbers engaged in it, or for the patriotism and heroism displayed.”
—Henry David Thoreau (1817–1862)
“Whenever we read the obscene stories, the voluptuous debaucheries, the cruel and torturous executions, the unrelenting vindictiveness, with which more than half the Bible is filled, it would be more consistent that we called it the word of a demon than the Word of God. It is a history of wickedness that has served to corrupt and brutalize mankind.”
—Thomas Paine (1737–1809)