History
The LE cell was discovered in bone marrow in 1948 by Hargraves et al. This was the first indication that processes affecting the cell nucleus were responsible for lupus erythematosus (LE). In the 1950s, progressively more sensitive and specific ANA serology tests became available.
Read more about this topic: Anti-nuclear Antibody
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“No matter how vital experience might be while you lived it, no sooner was it ended and dead than it became as lifeless as the piles of dry dust in a school history book.”
—Ellen Glasgow (1874–1945)
“Philosophy of science without history of science is empty; history of science without philosophy of science is blind.”
—Imre Lakatos (1922–1974)
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—Derek Wall (b. 1965)