Associated Diseases
The normal titer of ANA is 1:40 or less. Higher titers are indicative of an autoimmune disease. The presence of ANA is indicative of lupus erythematosus (present in 80-90% of cases), though they also appear in some other auto-immune diseases such as Sjögren's syndrome (60%), rheumatoid arthritis (30-40%), autoimmune hepatitis, scleroderma and polymyositis & dermatomyositis (30%), and various non-rheumatological conditions associated with tissue damage. Other conditions with high ANA titre include Addison disease, Idiopathic thrombocytopenic purpura (ITP), Hashimoto's, Autoimmune hemolytic anemia, Type I diabetes mellitus, Mixed connective tissue disorder (MCTD).
Read more about this topic: Anti-nuclear Antibody
Famous quotes containing the word diseases:
“Even diseases have lost their prestige, there aren’t so many of them left.... Think it over ... no more syphilis, no more clap, no more typhoid ... antibiotics have taken half the tragedy out of medicine.”
—Louis-Ferdinand Céline (1894–1961)
“Arrogance, pedantry, and dogmatism ... the occupational diseases of those who spend their lives directing the intellects of the young.”
—Henry S. Canby (1878–1961)