Anthranilate Synthase

In enzymology, an anthranilate synthase (EC is an enzyme that catalyzes the chemical reaction

chorismate + L-glutamine anthranilate + pyruvate + L-glutamate

Thus, the two substrates of this enzyme are chorismate and L-glutamine, whereas its 3 products are anthranilate, pyruvate, and L-glutamate.

This enzyme belongs to the family of lyases, to be specifica the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is chorismate pyruvate-lyase (amino-accepting; anthranilate-forming). Other names in common use include anthranilate synthetase, chorismate lyase, and chorismate pyruvate-lyase (amino-accepting). This enzyme participates in phenylalanine, tyrosine and tryptophan biosynthesis and two-component system - general.

Read more about Anthranilate Synthase:  Structural Studies