"The Widowmaker"
Because the LAD provides much of the bloodflow for the left ventricle, which in turn provides much of the propulsive force for ejecting oxygenated blood to systemic circulation via the aorta, blockage of this artery is particularly associated with mortality. In the medical community ischemic heart attacks associated with this blood vessel are colloquially called "the Widowmaker."
Read more about this topic: Anterior Interventricular Branch Of Left Coronary Artery