Longevity Promotion
Knockout of the Agtr1a gene that encodes AT1 results in marked prolongation of the life span of mice by 26% compared to controls. The likely mechanism is reduction of oxidative damage ( especially to mitochondria ) and overexpression of renal prosurvival genes. The ARBs seem to have the same effect.
Read more about this topic: Angiotensin II Receptor Antagonist
Famous quotes containing the words longevity and/or promotion:
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—Ralph Waldo Emerson (1803–1882)
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—Rutherford Birchard Hayes (1822–1893)