Andrey Semyonov may refer to:
- Andrei Semenov (fighter) (born 1977), Russian mixed martial arts fighter
- Andrey Semyonov-Tyan-Shansky (1866–1942), Russian entomologist and beetle expert
- Andrei Sergeyevich Semyonov (born 1989), Russian football player
- Andrei Igorevich Semyonov (born 1992), Russian football player
- Andrey Semyonov (athlete)