Signs and Symptoms
It occurs in both nodal and extranodal locations. It typically presents at a late stage and is often associated with systemic symptoms ("B symptoms").
Granulomas may be present.
Read more about this topic: Anaplastic Large-cell Lymphoma
Famous quotes containing the words signs and, signs and/or symptoms:
“For Jews demand signs and Greeks desire wisdom, but we proclaim Christ crucified, a stumbling block to Jews and foolishness to Gentiles...”
—Bible: New Testament, 1 Corinthians 1:22-3.
“Cows wandered through the streets.... Vegetables grew chiefly in cans, and stream-beds and cañons glittered with these omnipresent signs of civilization.”
—Administration in the State of Colo, U.S. public relief program (1935-1943)
“The human condition is such that pain and effort are not just symptoms which can be removed without changing life itself; they are the modes in which life itself, together with the necessity to which it is bound, makes itself felt. For mortals, the “easy life of the gods” would be a lifeless life.”
—Hannah Arendt (1906–1975)