History
| Year | Event |
|---|---|
| 1824 | Charles Bell writes a report about ALS. |
| 1850 | English scientist Augustus Waller describes the appearance of shriveled nerve fibers |
| 1869 | French doctor Jean-Martin Charcot first describes ALS in scientific literature |
| 1881 | "Amyotrophic Lateral Sclerosis" is translated into English and published in a three-volume edition of Lectures on the Diseases of the Nervous System |
| 1939 | ALS becomes a cause célèbre in the United States when baseball legend Lou Gehrig's career—and, two years later, his life—is ended by the disease. He gives his farewell speech on 4 July 1939. |
| 1950s | ALS epidemic occurs among the Chamorro people on Guam |
| 1991 | Researchers link chromosome 21 to FALS (Familial ALS) |
| 1993 | SOD1 gene on chromosome 21 found to play a role in some cases of FALS |
| 1996 | Rilutek becomes the first FDA-approved drug for ALS |
| 1998 | The El Escorial criteria is developed as the standard for classifying ALS patient in clinical research |
| 1999 | The revised ALS Functional Rating Scale (ALSFRS-R) is published and soon becomes a gold standard measure for rating decline in ALS patient in clinical research |
| 2011 | Noncoding repeat expansions in C9ORF72 are found to be a major cause of ALS and frontotemporal dementia |
Read more about this topic: Amyotrophic Lateral Sclerosis
Famous quotes containing the word history:
“All history is a record of the power of minorities, and of minorities of one.”
—Ralph Waldo Emerson (1803–1882)
“The history of all countries shows that the working class exclusively by its own effort is able to develop only trade-union consciousness.”
—Vladimir Ilyich Lenin (1870–1924)
“Well, for us, in history where goodness is a rare pearl, he who was good almost takes precedence over he who was great.”
—Victor Hugo (1802–1885)