Amyotrophic Lateral Sclerosis - History

History

Timeline
Year Event
1824 Charles Bell writes a report about ALS.
1850 English scientist Augustus Waller describes the appearance of shriveled nerve fibers
1869 French doctor Jean-Martin Charcot first describes ALS in scientific literature
1881 "Amyotrophic Lateral Sclerosis" is translated into English and published in a three-volume edition of Lectures on the Diseases of the Nervous System
1939 ALS becomes a cause célèbre in the United States when baseball legend Lou Gehrig's career—and, two years later, his life—is ended by the disease. He gives his farewell speech on 4 July 1939.
1950s ALS epidemic occurs among the Chamorro people on Guam
1991 Researchers link chromosome 21 to FALS (Familial ALS)
1993 SOD1 gene on chromosome 21 found to play a role in some cases of FALS
1996 Rilutek becomes the first FDA-approved drug for ALS
1998 The El Escorial criteria is developed as the standard for classifying ALS patient in clinical research
1999 The revised ALS Functional Rating Scale (ALSFRS-R) is published and soon becomes a gold standard measure for rating decline in ALS patient in clinical research
2011 Noncoding repeat expansions in C9ORF72 are found to be a major cause of ALS and frontotemporal dementia

Read more about this topic:  Amyotrophic Lateral Sclerosis

Famous quotes containing the word history:

    The custard is setting; meanwhile
    I not only have my own history to worry about
    But am forced to fret over insufficient details related to large
    Unfinished concepts that can never bring themselves to the point
    Of being, with or without my help, if any were forthcoming.
    John Ashbery (b. 1927)

    The history of the past is but one long struggle upward to equality.
    Elizabeth Cady Stanton (1815–1902)

    Yet poetry, though the last and finest result, is a natural fruit. As naturally as the oak bears an acorn, and the vine a gourd, man bears a poem, either spoken or done. It is the chief and most memorable success, for history is but a prose narrative of poetic deeds.
    Henry David Thoreau (1817–1862)