History
| Year | Event |
|---|---|
| 1824 | Charles Bell writes a report about ALS. |
| 1850 | English scientist Augustus Waller describes the appearance of shriveled nerve fibers |
| 1869 | French doctor Jean-Martin Charcot first describes ALS in scientific literature |
| 1881 | "Amyotrophic Lateral Sclerosis" is translated into English and published in a three-volume edition of Lectures on the Diseases of the Nervous System |
| 1939 | ALS becomes a cause célèbre in the United States when baseball legend Lou Gehrig's career—and, two years later, his life—is ended by the disease. He gives his farewell speech on 4 July 1939. |
| 1950s | ALS epidemic occurs among the Chamorro people on Guam |
| 1991 | Researchers link chromosome 21 to FALS (Familial ALS) |
| 1993 | SOD1 gene on chromosome 21 found to play a role in some cases of FALS |
| 1996 | Rilutek becomes the first FDA-approved drug for ALS |
| 1998 | The El Escorial criteria is developed as the standard for classifying ALS patient in clinical research |
| 1999 | The revised ALS Functional Rating Scale (ALSFRS-R) is published and soon becomes a gold standard measure for rating decline in ALS patient in clinical research |
| 2011 | Noncoding repeat expansions in C9ORF72 are found to be a major cause of ALS and frontotemporal dementia |
Read more about this topic: Amyotrophic Lateral Sclerosis
Famous quotes containing the word history:
“... in a history of spiritual rupture, a social compact built on fantasy and collective secrets, poetry becomes more necessary than ever: it keeps the underground aquifers flowing; it is the liquid voice that can wear through stone.”
—Adrienne Rich (b. 1929)
“the future is simply nothing at all. Nothing has happened to the present by becoming past except that fresh slices of existence have been added to the total history of the world. The past is thus as real as the present.”
—Charlie Dunbar Broad (1887–1971)
“Don’t you realize that this is a new empire? Why, folks, there’s never been anything like this since creation. Creation, huh, that took six days, this was done in one. History made in an hour. Why it’s a miracle out of the Old Testament!”
—Howard Estabrook (1884–1978)