History
| Year | Event |
|---|---|
| 1824 | Charles Bell writes a report about ALS. |
| 1850 | English scientist Augustus Waller describes the appearance of shriveled nerve fibers |
| 1869 | French doctor Jean-Martin Charcot first describes ALS in scientific literature |
| 1881 | "Amyotrophic Lateral Sclerosis" is translated into English and published in a three-volume edition of Lectures on the Diseases of the Nervous System |
| 1939 | ALS becomes a cause célèbre in the United States when baseball legend Lou Gehrig's career—and, two years later, his life—is ended by the disease. He gives his farewell speech on 4 July 1939. |
| 1950s | ALS epidemic occurs among the Chamorro people on Guam |
| 1991 | Researchers link chromosome 21 to FALS (Familial ALS) |
| 1993 | SOD1 gene on chromosome 21 found to play a role in some cases of FALS |
| 1996 | Rilutek becomes the first FDA-approved drug for ALS |
| 1998 | The El Escorial criteria is developed as the standard for classifying ALS patient in clinical research |
| 1999 | The revised ALS Functional Rating Scale (ALSFRS-R) is published and soon becomes a gold standard measure for rating decline in ALS patient in clinical research |
| 2011 | Noncoding repeat expansions in C9ORF72 are found to be a major cause of ALS and frontotemporal dementia |
Read more about this topic: Amyotrophic Lateral Sclerosis
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—Richard M. Nixon (1913–1995)
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—Albert Camus (1913–1960)
“I am ashamed to see what a shallow village tale our so-called History is. How many times must we say Rome, and Paris, and Constantinople! What does Rome know of rat and lizard? What are Olympiads and Consulates to these neighboring systems of being? Nay, what food or experience or succor have they for the Esquimaux seal-hunter, or the Kanaka in his canoe, for the fisherman, the stevedore, the porter?”
—Ralph Waldo Emerson (1803–1882)