Agents Requiring Activation
Some of the substances require conversion into active substances in vivo (e.g., cyclophosphamide).
Cyclophosphamide is one of the most potent immunosuppressive substances. In small dosages, it is very efficient in the therapy of systemic lupus erythematosus, autoimmune hemolytic anemias, Wegener's granulomatosis, and other autoimmune diseases. High dosages cause pancytopenia and hemorrhagic cystitis.
Read more about this topic: Alkylating Antineoplastic Agent
Famous quotes containing the words agents and/or requiring:
“The Times are the masquerade of the eternities; trivial to the dull, tokens of noble and majestic agents to the wise; the receptacle in which the Past leaves its history; the quarry out of which the genius of today is building up the Future.”
—Ralph Waldo Emerson (1803–1882)
“Compared to football, baseball is almost an Oriental game, minimizing individual stardom, requiring a wide range of aggressive and defensive skills, and filled with long periods of inaction and irresolution. It has no time limitations. Football, on the other hand, has immediate goals, resolution on every single play, and a lot of violence—itself a highlight. It has clearly distinguishable hierarchies: heroes and drones.”
—Jerry Mander, U.S. advertising executive, author. Four Arguments for the Elimination of Television, ch. 15, Morrow (1978)