Agents Requiring Activation
Some of the substances require conversion into active substances in vivo (e.g., cyclophosphamide).
Cyclophosphamide is one of the most potent immunosuppressive substances. In small dosages, it is very efficient in the therapy of systemic lupus erythematosus, autoimmune hemolytic anemias, Wegener's granulomatosis, and other autoimmune diseases. High dosages cause pancytopenia and hemorrhagic cystitis.
Read more about this topic: Alkylating Antineoplastic Agent
Famous quotes containing the words agents and/or requiring:
“Luckless is the country in which the symbols of procreation are the objects of shame, while the agents of destruction are honored! And yet you call that member your pudendum, or shameful part, as if there were anything more glorious than creating life, or anything more atrocious than taking it away.”
—Savinien Cyrano De Bergerac (1619–1655)
“Compared to football, baseball is almost an Oriental game, minimizing individual stardom, requiring a wide range of aggressive and defensive skills, and filled with long periods of inaction and irresolution. It has no time limitations. Football, on the other hand, has immediate goals, resolution on every single play, and a lot of violence—itself a highlight. It has clearly distinguishable hierarchies: heroes and drones.”
—Jerry Mander, U.S. advertising executive, author. Four Arguments for the Elimination of Television, ch. 15, Morrow (1978)