Agents Requiring Activation
Some of the substances require conversion into active substances in vivo (e.g., cyclophosphamide).
Cyclophosphamide is one of the most potent immunosuppressive substances. In small dosages, it is very efficient in the therapy of systemic lupus erythematosus, autoimmune hemolytic anemias, Wegener's granulomatosis, and other autoimmune diseases. High dosages cause pancytopenia and hemorrhagic cystitis.
Read more about this topic: Alkylating Antineoplastic Agent
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