Agents Acting Nonspecifically
Some alkylating agents are active under conditions present in cells; and the same mechanism that makes them toxic allows them to be used as anti-cancer drugs. They stop tumor growth by crosslinking guanine nucleobases in DNA double-helix strands, directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. These drugs act nonspecifically.
Read more about this topic: Alkylating Antineoplastic Agent
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“Luckless is the country in which the symbols of procreation are the objects of shame, while the agents of destruction are honored! And yet you call that member your pudendum, or shameful part, as if there were anything more glorious than creating life, or anything more atrocious than taking it away.”
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