Isolation and Description of Nucleobases
In 1883, Kossel left Strasburg to become Director of the Chemistry Division of the Physiological Institute at the University of Berlin. In this post, he succeeded Eugen Baumann and worked under the supervision of Emil du Bois-Reymond.
Kossel continued his previous work on the nucleic acids. During the period 1885 to 1901, he was able to isolate and name its five constituent organic compounds: adenine, cytosine, guanine, thymine, and uracil. These compounds are now known collectively as nucleobases, and they provide the molecular structure necessary in the formation of stable DNA and RNA molecules.
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