Function
It catalyzes the transfer of an amino group from alanine to α-ketoglutarate, the products of this reversible transamination reaction being pyruvate and glutamate.
- glutamate + pyruvate ⇌ α-ketoglutarate + alanine
ALT (and all transaminases) require the coenzyme pyridoxal-phosphate, which is converted into pyridoxamine in the first phase of the reaction, when an amino acid is converted into a keto acid.
Read more about this topic: Alanine Transaminase
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