AEL may refer to:
- Acute Eosinophilic Leukemia, a form of leukemia
- AEL 1964 BC, AE Larissa GS, Greece professional basketball club
- AEL 1964 FC, or Larissa, a Greek football club
- AEL FC, a Cypriot football club
- African Explosives, a mining services company headquartered in Johannesburg
- Arab European League, in Belgium and the Netherlands
- Asiatic Exclusion League, in the United States and Canada
- Association Electronique Libre
- Proteas EKA AEL, a Cypriot basketball club