AGE Formation
AGEs may be formed external to the body (exogenously) by heating (e.g., cooking); or inside the body (endogenously) through normal metabolism and aging. Under certain pathologic conditions (e.g., oxidative stress due to hyperglycemia in patients with diabetes), AGE formation can be increased beyond normal levels. AGEs are now known to play a role as proinflammatory mediators in gestational diabetes as well.
Read more about this topic: Advanced Glycation End-product
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