Prognosis
ACC, generally, carries a poor prognosis and is unlike most tumours of the adrenal cortex, which are benign (adenomas) and only occasionally cause Cushing's syndrome. Five-year disease-free survival for a complete resection of a stage I-III ACC is approximately 30%. The most important prognostic factors are age of the patient and stage of the tumor. Poor prognostic factors: mitotic activity, venous invasion, weight of 50g+; diameter of 6.5 cm+, Ki-67/MIB1 labeling index of 4%+, p53+. Research Fellow Sachin H. Jain, Professor Michael E. Porter, and colleagues at Harvard Business School have published an extensive business school case study documenting the care process for a single patient with adrenal cortical carcinoma, "Ledina Lushko: Navigating Health Care Delivery."
Read more about this topic: Adrenocortical Carcinoma