ADK may refer to:

  • ADK (automobile), a Belgian automobile manufactured between 1923 and 1930
  • ADK (company) or Alpha Denshi, a video game development company in Japan
  • Adenylate kinase, a phosphotransferase enzyme that plays an important role in cellular energy homeostasis
  • Adirondack Mountain Club, a nonprofit organization in New York, New Jersey and Massachusetts
  • Aggressors of Dark Kombat, an arcade game released by SNK and developed by Alpha Denshi Corp
  • Android Open Accessory Development Kit
  • Asatsu DK, a Japanese advertising firm
  • NZR ADK class
  • Adak Airport's IATA Code
  • Ardwick railway station's National Rail code
  • ADK, a model for tunnel ionization
  • Adk, a village in Razavi Khorasan Province, Iran