Proteins
Adherens junctions are composed of the following proteins:
- cadherins. The cadherins are a family of transmembrane proteins that form homodimers in a calcium-dependent manner with other cadherin molecules on adjacent cells.
- p120 (sometimes called delta catenin) binds the juxtamembrane region of the cadherin.
- β-catenin or gamma-catenin (plakoglobin) binds the catenin-binding region of the cadherin.
- α-catenin binds the cadherin indirectly via β-catenin or plakoglobin and links the actin cytoskeleton with cadherin.
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