Substrate and Products
The reaction catalyzed is:
2 ADP ⇔ ATP + AMP
The equilibrium constant varies with condition, but is close to 1. Thus, the ΔGo for this reaction is close to zero. In muscle of a variety of species of vertebrates and invertebrates, the concentration of ATP is typically 7-10 times that of ADP, and usually greater than 100 times that of AMP. The rate of oxidative phosphorylation is controlled by the availability of ADP. Thus, the mitochondrion attempts to keep ATP levels high due to the combined action of adenylate kinase and the controls on oxidative phosphorylation.
Read more about this topic: Adenylate Kinase
Famous quotes containing the word products:
“It seemed there was a sort of poisoning, an auto-infection of the organisms, so Dr. Krokowski said; it was caused by the disintegration of a substance ... and the products of this disintegration operated like an intoxicant upon the nerve-centres of the spinal cord, with an effect similar to that of certain poisons, such as morphia, or cocaine.”
—Thomas Mann (1875–1955)