Adenosine Monophosphate Deaminase Deficiency Type 1 - Potential Complications

Potential Complications

There is an increased risk that statin (cholesterol reducing drugs) will cause myopathy (muscle weakness) in individuals with MADD.

Anesthesia has the potential to cause malignant hyperthermia, an uncontrolled increase in body temperature, and permanent muscle damage in patients with MADD. Individuals with MADD are advised to notify their an anesthesiologist about their condition prior to surgery.

In most where myopathy is present with MADD, a second muscle disease is present and symptoms are worse than either disease in isolation.

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