Acyl Halide - Preparation

Preparation

A common laboratory method for the synthesis of acyl halides entails reaction of carboxylic acids with reagents such as thionyl chloride or phosphorus pentachloride for acyl chlorides, phosphorus pentabromide for acyl bromides and cyanuric fluoride for acyl fluorides.

Aromatic acyl chlorides can be prepared by chloroformylation, a specific type of Friedel-Crafts acylation using formaldehyde as the reagent.

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