Safety of AHCC
AHCC has been studied for safety in human trials as well as safety with conventional chemotherapy.
Safety studies have been conducted according to GLP standards. The LD50 according to tests with SD rats is > 12,500 mg/kg by oral administration. Toxic activity was not seen even in intra-peritoneal administration of AHCC: Male: LD50 = 8,490 mg/kg, estimated intraperitoneal fatal dose =7,430 mg/kg Female: LD50 = 9,849 mg/kg and estimated fatal dose = 8,340 mg/kg
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